notch pathway signaling receptor inhibitor Search Results


gene exp egf hs01099999 m1  (Thermo Fisher)
95
Thermo Fisher gene exp egf hs01099999 m1
Gene Exp Egf Hs01099999 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/notch+pathway+signaling+receptor+inhibitor/Gene+Exp%2E+EGF%2C+Hs01099999_m1/pmc11362533__41420_2024_2148_MOESM2_ESM-73-46--1
Average 95 stars, based on 1 article reviews
gene exp egf hs01099999 m1 - by Bioz Stars, 2026-09
95/100 stars
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notch1 csl reporter kit  (BPS Bioscience)
94
BPS Bioscience notch1 csl reporter kit
Notch1 Csl Reporter Kit, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/notch+pathway+signaling+receptor+inhibitor/Notch1+Pathway+Reporter+Kit/pmc04398028-283-19-22
Average 94 stars, based on 1 article reviews
notch1 csl reporter kit - by Bioz Stars, 2026-09
94/100 stars
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notch signal pathway inhibitor dapt gsi ix  (Selleck Chemicals)
96
Selleck Chemicals notch signal pathway inhibitor dapt gsi ix
TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by Notch signal pathway. A, The representative plots of flow cytometry analysis and (B) the statistics of CD34 + cell apoptosis rates in the presence or absence of TNFSF15 (2 µg/mL). The experiment was repeated for three times (n = 3). C, The representative plots of flow cytometry analysis and (D) the statistics of CD34 + cell cycle distribution of G0/G1, S and G2‐M phase in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). The experiment was repeated for three times. E, The percentage of G0 phase was detected in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium by Ki67/PI double staining assay (n = 3). F, The gene expression of c‐myc in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). G, The gene expression of hes1 in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). H, Western blotting analysis of Notch signal pathway proteins including c‐myc, hes1, Notch1 and NCID in CD34 + cells treated with TNFSF15 at indicated concentrations for 7 d in expansion medium. I, The absolute number of CD34 + CD49f + cells after cultured with combination of TNFSF15 (2 µg/mL) and <t>DAPT</t> (0.5 µmol/L) for 7 d in expansion medium (n = 3)
Notch Signal Pathway Inhibitor Dapt Gsi Ix, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/notch+pathway+signaling+receptor+inhibitor/DAPT/pmc07576288-35-6-15
Average 96 stars, based on 1 article reviews
notch signal pathway inhibitor dapt gsi ix - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier

Image Search Results


TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by Notch signal pathway. A, The representative plots of flow cytometry analysis and (B) the statistics of CD34 + cell apoptosis rates in the presence or absence of TNFSF15 (2 µg/mL). The experiment was repeated for three times (n = 3). C, The representative plots of flow cytometry analysis and (D) the statistics of CD34 + cell cycle distribution of G0/G1, S and G2‐M phase in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). The experiment was repeated for three times. E, The percentage of G0 phase was detected in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium by Ki67/PI double staining assay (n = 3). F, The gene expression of c‐myc in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). G, The gene expression of hes1 in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). H, Western blotting analysis of Notch signal pathway proteins including c‐myc, hes1, Notch1 and NCID in CD34 + cells treated with TNFSF15 at indicated concentrations for 7 d in expansion medium. I, The absolute number of CD34 + CD49f + cells after cultured with combination of TNFSF15 (2 µg/mL) and DAPT (0.5 µmol/L) for 7 d in expansion medium (n = 3)

Journal: Journal of Cellular and Molecular Medicine

Article Title: TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by activating Notch signal pathway

doi: 10.1111/jcmm.15626

Figure Lengend Snippet: TNFSF15 facilitates human umbilical cord blood haematopoietic stem cell expansion by Notch signal pathway. A, The representative plots of flow cytometry analysis and (B) the statistics of CD34 + cell apoptosis rates in the presence or absence of TNFSF15 (2 µg/mL). The experiment was repeated for three times (n = 3). C, The representative plots of flow cytometry analysis and (D) the statistics of CD34 + cell cycle distribution of G0/G1, S and G2‐M phase in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). The experiment was repeated for three times. E, The percentage of G0 phase was detected in the presence or absence of TNFSF15 (2 µg/mL) for 7 d in expansion medium by Ki67/PI double staining assay (n = 3). F, The gene expression of c‐myc in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). G, The gene expression of hes1 in CD34 + CD38 − CD90 + CD45RA − CD49f + cells after the treatment of TNFSF15 (2 µg/mL) for 7 d in expansion medium (n = 3). H, Western blotting analysis of Notch signal pathway proteins including c‐myc, hes1, Notch1 and NCID in CD34 + cells treated with TNFSF15 at indicated concentrations for 7 d in expansion medium. I, The absolute number of CD34 + CD49f + cells after cultured with combination of TNFSF15 (2 µg/mL) and DAPT (0.5 µmol/L) for 7 d in expansion medium (n = 3)

Article Snippet: The small compounds SR1, UM171 and Notch signal pathway inhibitor DAPT (GSI‐IX) were purchased in Selleck.

Techniques: Flow Cytometry, Double Staining, Gene Expression, Western Blot, Cell Culture